Test failure of the deletion/duplication, also known as Copy Number Variation (CNV), analysis occurs in a very small percentage of cases. The specific cause for CNV test failures is speculative and it is likely due to a variety of specific scenarios that have accumulated to affect the DNA quality/quantity in a manner that caused the failure. These factors may include more severe and/or metastatic disease. underlying hematological malignancy, age of sample, sample conditions, etc. Recent chemotherapy, or other treatments that may have decreased white blood cell counts and/or caused DNA damage, may also cause test failure. If the failure occurred with a blood or saliva sample, we recommend submitting a new, preferably blood, sample.
Articles in this section
- What are possible explanations for sample failures?
- What are the specimen requirements?
- Does Invitae provide specimen collection kits?
- What paperwork is required with each specimen?
- Does Invitae accept DNA extracted in other laboratories?
- Can you arrange a blood draw for my patient?
- Do you accept post-mortem specimens?
- Do you accept fetal specimens?
- What is the difference between saliva and assisted saliva?
- Are there any special instructions for saliva specimens?