Invitae offers two types of PGT:
PGT for chromosomal aneuploidy (PGT-A, also known as PGS)
- This test identifies embryos with the correct number of chromosomes to improve the chances of a successful pregnancy.
- When an embryo has extra or missing chromosomes, that’s a condition known as aneuploidy. Most aneuploid embryos do not result in a healthy live birth: many lead to spontaneous miscarriage, some fail to implant in the uterus, and some result in a baby with birth defects, intellectual disability, and/or other health problems. Aneuploidy occurs across all age groups, but after a woman reaches age 35, the proportion of aneuploid embryos increases rapidly.
PGT for structural chromosome rearrangements/translocations (PGT-SR)
- This test evaluates embryos for unbalanced structural chromosome rearrangements (translocations). It is useful when a chromosomal translocation has previously been identified in the family.
- Invitae’s PGT-SR also screens for chromosomal aneuploidy.
- PGT-SR cases are accepted on a case-by-case basis. A referral form and documentation of the known translocation (karyotype) must be submitted, reviewed, and approved by the Invitae medical team to determine eligibility prior to testing.