Our confirmation for SNVs and indels is performed with Sanger sequencing or PacBio long-read sequencing, depending on the need. For STAT tests that require a fast turnaround time, we use Sanger sequencing exclusively. Beginning in May 2016, other tests are confirmed by using PacBio technology. Before launching this assay, we validated and then implemented a standard PacBio technique of circularizing the DNA and sequencing the template dozens of times, thereby lowering the error rate for PacBio sequencing to a level sufficient for clinical use. For more information, please visit our Validation studies page, which includes a link to our confirmation testing white paper.