Yes, Invitae does confirm variants for both panel and exome testing. We perform orthogonal confirmation of clinically significant findings and have done so since we first started our clinical testing service. The confirmation techniques we use include Sanger sequencing, PacBio sequencing of circularized amplicons, array comparative genome hybridization (aCGH), and multiplex ligation-dependent probe amplification (MLPA). To date we’ve performed confirmation on more than 8,000 SNPs and small indels, and more than 1,000 copy number variants. These variants represent what would ordinarily be found in a population of approximately 70,000 individuals undergoing genetic testing. For more information, please visit our Validation studies page, which includes a link to our confirmation testing white paper.