Invitae believes knowledge is more valuable when shared. We currently contribute variants to ClinVar approximately every 6 months. It takes several months for ClinVar to process and post our submissions. In addition, we have created ClinVitae, a database of clinically observed genetic variants aggregated from public sources. ClinVitae provides a fast and intuitive engine for searching for variants across all these sources simultaneously. It is operated and made freely available by Invitae at clinvitae.invitae.com.
Clinvitae aggregates data from the following sources:
- ClinVar, including variants contributed by Invitae
- Emory Genetics Variant Classification Catalog
- ARUP Mutation Databases
- Carver Mutation Database
- Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer
Invitae is committed to making our clinically observed variants publicly available.
We do not add our internally observed variants directly to ClinVitae; we contribute to ClinVar and then ClinVar populates ClinVitae.